Use of a TT virus ORF1 recombinant protein to detect anti-TT virus antibodies in human sera

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[Susceptibility of TT virus to interferon therapy].

A novel single stranded DNA virus, TT virus, associated with posttransfusion hepatitis was identified. The impact of the virus on development of chronic liver diseases and the susceptibility of the virus to interferon therapy has not been investigated. We retrospectively analyzed blood samples from 16 patients infected with both hepatitis C virus and TT virus who were treated by interferon. TT ...

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Pathological changes of renal epithelial cells in mice transgenic for the TT virus ORF1 gene.

TT virus (TTV) is a newly identified human DNA virus of the family Circoviridae. Its genome consists of six putative open reading frames (ORFs). TTV was isolated originally from a patient with cryptogenic hepatitis and the association of TTV with hepatitis has been studied extensively, while its significance in other diseases is unknown. To examine the pathogenicity of TTV, mice transgenic for ...

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TT virus contaminates first-generation recombinant factor VIII concentrates.

Recombinant factor VIII and factor IX concentrates, human-plasma-derived albumin, and samples from previously untreated patients with hemophilia were examined for the presence of TT virus (TTV) by using polymerase chain reaction testing. Blood samples from the patients were obtained prospectively before and every 3 to 6 months after therapy was begun. TTV was detected in 23.5% of the recombinan...

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TT virus in bone marrow transplant recipients.

TT virus (TTV) is a newly discovered transfusion-transmissible DNA virus, which may cause posttransfusion hepatitis. The virus was detected in 12% of Japanese blood donors. The aim of the study is to investigate the prevalence and clinical influence of TTV in bone marrow transplant (BMT) recipients. Sera from 25 BMT recipients obtained 6 to 12 weeks after the transplant were examined for TTV-DN...

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NOTE Virology TT Virus Infection in Gibbons

TT virus (TTV) is not only an infectious agent of worldwide distribution but has also been demonstrated in various non-human primates in addition to humans. In the present study, we subjected the sera of 67 gibbons to PCR and nucleotide sequencing, with subsequent phylogenetic analysis to determine the nature of the relationship between TTV found in humans and non-human primates. We discovered ...

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ژورنال

عنوان ژورنال: Journal of General Virology

سال: 2000

ISSN: 0022-1317,1465-2099

DOI: 10.1099/0022-1317-81-12-2949